Tricarboxylic acids and derivatives
Medchemexpress LLC Adenosine 5'-(α,β-methylene)diphosphate triammonium | 00-00-0 | MFCD00042991 | 99.9% | 476.32 g·mol⁻¹ | C11H26N8O9P2 | 5 MG
MethADP triammonium (Adenosine 5'-(α,β-methylene)diphosphate triammonium) is a nucleotide analog used as a selective CD73 inhibitor for research into the ATP-adenosine pathway. Supplied as the triammonium salt, it is provided for laboratory research use in solid or solution form.
- CD73 inhibitor for ATP-adenosine pathway studies.
- High purity: 99.9%.
- Molecular weight 476.32 g·mol⁻¹; chemical formula C11H26N8O9P2.
- Appearance: off-white to light yellow solid.
- Storage: solid at 4°C; in solvent -80°C up to 6 months, -20°C up to 1 month.
- Available in small solid quantities and as a 10 mM solution.
![Medchemexpress LLC Acetic acid, 2-[2-(2-azidoethoxy)ethoxy]- | 882518-90-3 | 99.0% | 189.17 | 1 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC Acetic acid, 2-[2-(2-azidoethoxy)ethoxy]- | 882518-90-3 | 99.0% | 189.17 | 1 MG
Azido-PEG2-CH2COOH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an Azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc)
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Can be used in the synthesis of PROTACs
- PROTACs utilize the intracellular ubiquitin-proteasome system to degrade target proteins
Medchemexpress LLC Acetic acid, 2-[2-(2-azidoethoxy)ethoxy]- | 882518-90-3 | 99.03% | 189.17 | 10 MG
Azido-PEG2-CH2COOH is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. It also functions as a click chemistry reagent, featuring an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Can be used in the synthesis of PROTACs.
- Functions as a click chemistry reagent.
- Azide group enables copper-catalyzed azide-alkyne cycloaddition.
- Can undergo strain-promoted alkyne-azide cycloaddition with DBCO or BCN groups.
Medchemexpress LLC Tos-peg3-ch2cooh | 1581248-63-6 | 100 MG
Tos-PEG3-CH2COOH is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. PROTACs are molecules that leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins. They consist of two different ligands connected by a linker; one ligand binds to an E3 ubiquitin ligase, and the other binds to the target protein, facilitating its degradation.
- Utilizes the ubiquitin-proteasome system for selective protein degradation.
- Acts as a linker in the construction of degraders.
Medchemexpress LLC Arimoclomol citrate | 368860-21-3 | 99.8% | 505.90 g·mol⁻¹ | C20H28ClN3O10 | 1 ML
Arimoclomol citrate is the citrate salt of arimoclomol, a heat-shock protein (HSP) co-inducer used in research to enhance Hsp expression, reduce protein aggregation, and study neurodegenerative conditions such as Niemann-Pick disease type C. Supplied for in vitro and preclinical laboratory work, it is available as a solution in DMSO and in multiple solid pack sizes.
- High reported purity (99.8%).
- Supplied as a 10 mM solution in DMSO for ready use.
- Also available in solid form for flexible dosing and formulation.
- Molecular weight 505.90 g·mol⁻¹ for stoichiometric calculations.
- Facilitates studies of Hsp induction and protein aggregation.
- Suitable for in vitro and preclinical model applications.
Medchemexpress LLC CH2COOH-PEG6-CH2COOH 250mg
CH2COOH-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]